GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs11871801 | 1 | rs6503703 | chr17:40592207 | NAGLU | chr17:40687951-40696464:+ | -0.22 | -4.7 | 3.4E-6 | Crohn's disease |
| THCA | cis | rs11871801 | 1 | rs6503703 | chr17:40592207 | TUBG2 | chr17:40811266-40819023:+ | -0.24 | -5.63 | 3.08E-8 | Crohn's disease |
| THCA | cis | rs11871801 | 1 | rs6503704 | chr17:40592253 | NAGLU | chr17:40687951-40696464:+ | -0.22 | -4.65 | 4.28E-6 | Crohn's disease |
| THCA | cis | rs11871801 | 1 | rs6503704 | chr17:40592253 | TUBG2 | chr17:40811266-40819023:+ | -0.23 | -5.45 | 8.03E-8 | Crohn's disease |
| THCA | cis | rs9303401 | 1 | rs6503877 | chr17:56841948 | SUPT4H1 | chr17:56422539-56429563:- | -0.17 | -4.21 | 3.07E-5 | Cognitive test performance |
| THCA | cis | rs9303401 | 1 | rs6503882 | chr17:56915761 | SUPT4H1 | chr17:56422539-56429563:- | -0.16 | -3.9 | 0.000109 | Cognitive test performance |
| THCA | cis | rs7223966 | 1 | rs6504167 | chr17:61693194 | FTSJ3 | chr17:61896795-61905031:- | 0.32 | 5.99 | 4.06E-9 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504167 | chr17:61693194 | MAP3K3 | chr17:61699775-61773669:+ | 0.28 | 5.59 | 3.79E-8 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504168 | chr17:61697469 | FTSJ3 | chr17:61896795-61905031:- | 0.34 | 6.35 | 5.09E-10 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504168 | chr17:61697469 | MAP3K3 | chr17:61699775-61773669:+ | 0.28 | 5.74 | 1.7E-8 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504169 | chr17:61709145 | FTSJ3 | chr17:61896795-61905031:- | 0.32 | 6.01 | 3.7E-9 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504169 | chr17:61709145 | MAP3K3 | chr17:61699775-61773669:+ | 0.28 | 5.66 | 2.63E-8 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504170 | chr17:61709168 | FTSJ3 | chr17:61896795-61905031:- | 0.31 | 5.97 | 4.53E-9 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504170 | chr17:61709168 | MAP3K3 | chr17:61699775-61773669:+ | 0.27 | 5.61 | 3.35E-8 | Body mass index |
| THCA | cis | rs7223966 | 1 | rs6504171 | chr17:61710010 | FTSJ3 | chr17:61896795-61905031:- | 0.3 | 5.78 | 1.32E-8 | Body mass index |